/
/ () / ZYVOX (Linezolid)
, , , - ; ; ; , Enterococcus faecalis faecium.
, 2 .
(12 ):
()
( )
/ 600
12
10-14
( )
( )*
( , )
/ 600
12
14-28
( 5 11 )**:
()
( )
/ 10 /
8
10-14
( )
( )*
( , )
/ 10 /
8
14-28
* , , .
** 7 ( 34 ) AUC, . 7 AUC .
600 2 .
/ 2 . - 30-120 .
, , . , 100%.
/ 30-120 . ! . 1 , . - ! - . !
15-25 . - . .
-
-
--
-
() / ZYVOX (Linezolid) . / , , . , , .
|
. / 50 .
Cheplapharm
|
8363 .
|
! |
|
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. / 450 / 60 .
Hexal AG
|
282602 .
|
! |
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. /. 20 / 8 .
Eli Lilly
|
38694 .
|
! |
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. - /. 300 / 1 .
Otsuka Pharmaceutical
|
108904 .
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! |
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- /. / . 70 / 1 .
Novartis
|
60944 .
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! |
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. 0,5 / 20 .
ratiopharm
|
6597 .
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! |
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. 30 , . / 1 .
Desitin
|
4507 .
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! |
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5 8 , . . / 1 .
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30 / 1 .
Kyberg Pharma
|
5516 .
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! |
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/ 50 / 1 .
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. . 20 / 10 .
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- /. 1,1 . / 100 .
Heel
|
40958 .
|
! |
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15 /2 , / 1 .
actrevo
|
11813 .
|
! |
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20 /2 , / 1 .
actrevo
|
16977 .
|
! |
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60 /3 , / 1 .
actrevo
|
52739 .
|
! |
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- /. . 0,05% 60 , . / 1 .
Leo Laboratories
|
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- . / . 25000 /2,5 , . / 2 .
Abiogen Pharma
|
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- . / . 50000 /2,5 , . / 2 .
Abiogen Pharma
|
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. - /. 1 , . / 1 .
Teva
|
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|
. 50 /100 / 28 .
Merck Sharp & Dohme
|
1693236 .
|
! |
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. 50 /100 / 14 .
Merck Sharp & Dohme
|
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- . 2 / - / . 100 / 1 .
Fresenius Kabi Norge
|
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. /. - /. 500 /10 (50 /), . / 1 .
AstraZeneca
|
365665 .
|
! |
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/ 60 .
Gepach International
|
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- /. 50 2 . / 1 .
Teva
|
6635 .
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! |
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/. , 400 / 1 .
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. 40 / 30 .
Actavis
|
4006 .
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! |
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. 40 / 50 .
Actavis
|
4456 .
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! |
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. 25 / 30 .
Actavis
|
3842 .
|
! |
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. 10 / 30 .
Intercept Pharmaceuticals
|
500524 .
|
! |
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. 5 / 30 .
Intercept Pharmaceuticals
|
498298 .
|
! |
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- . /. 0,1% . 1 / 10 .
|
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., /, 20 / 60 .
BMS
|
96055 .
|
! |
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- /. . . / 8 .
Weleda
|
5846 .
|
! |
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. /. . -. 50 / 100 .
Lannacher Heilmittel
|
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. . 10 / 100 .
Sanofi-Aventis
|
40959 .
|
! |
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|
- / . 30 /, 1 . . / 1 .
AstraZeneca
|
509627 .
|
! |
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. + 30 / 60 .
Gonadosan
|
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. / 30 .
Gonadosan
|
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- /. 8 / 3 .
Merck Serono
|
3938 .
|
! |
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- /. 40 / 1 .
Merck Serono
|
6409 .
|
! |
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- /. 4 / 3 .
Merck Serono
|
3638 .
|
! |
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. / 1 .
Teva
|
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|
. /. . 5 , . / 10 .
Sanofi-Aventis
|
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. 60 / 100 .
Forest Lab. UK
|
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7 14 / 1 .
Shaoxing Zhengde Surgical Dressing
|
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|
5 10 / 1 .
Shaoxing Zhengde Surgical Dressing
|
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|
5 10 / 1 .
|
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5 10 / 1 .
|
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5 10 / 1 .
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5 10 / 1 .
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5 7 / 1 .
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7 14 / 1 .
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7 14 / 1 .
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7 14 / 1 .
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5 10 / 1 .
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5 10 / 1 .
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7 14 / 1 .
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7 14 / 1 .
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5 10 / 1 .
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7 14 / 1 .
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7 14 / 1 .
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5 10 / 1 .
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3,5 / 1 .
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5 / 1 .
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3,5 , . . / 1 .
|
846 .
|
! |
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5 , . . / 1 .
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1 8 , . / 1 .
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1 10 , . . / 1 .
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1 10 , . . / 1 .
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1 10 , . . / 1 .
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1 8 , . . / 1 .
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1 8 , . . / 1 .
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1,5 10 , . . / 1 .
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1,5 10 , . . / 1 .
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1,5 10 , . . / 1 .
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1,5 8 c, . . / 1 .
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1,5 8 c, . . / 1 .
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1,5 8 c, . . / 1 .
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2 8 , . . / 1 .
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2 10 , . . / 1 .
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2 8 , . . / 1 .
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2,5 10 , . . / 1 .
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2,5 10 , . . / 1 .
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2,5 8 , . . / 1 .
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3 8 , . . / 1 .
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3 10 , . . / 1 .
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3 10 , . . / 1 .
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3 8 , . . / 1 .
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4 10 , . . / 1 .
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4 8 , . . / 1 .
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4 10 , . . / 1 .
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4 8 , . . / 1 .
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5 10 , . . / 1 .
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5 8 , . . / 1 .
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5 8 , . . / 1 .
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4 10 , . . / 1 .
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1 8 , / 1 .
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1,5 8 c, / 1 .
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2 8 , / 1 .
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